Characterization of the endocrine-metabolic and anthropometric profile in a group of patients diagnosed with polycystic ovarian syndrome.

Abstract

Polycystic ovarian syndrome (PCOS) is an endocrine-metabolic dysfunction that affects 6 to 10% of women of reproductive age. It is characterize by chronic anovulation, hyperandrogenism and the presence of metabolic complications such as obesity, dyslipidemia, arterial hypertension, coronary artery disease and fatty liver. The objective of this research was to characterize the endocrine-metabolic and anthropometric profile in a group of patients diagnosed with PCOS. The population consisted of 81 patients who attended the gynecologic clinic of the Urban Outpatient Type II "Dr. Ramón Gualdrón"from Barquisimeto-Lara State, of which only 50 patients met the criteria of the 2003 Rotterdam Consensus for the diagnosis of PCOS. According to the results of this study, the endocrine profile of the patients is characterized by normal levels of progesterone and free testosterone and insulin in the normal upper range; lipid profile within normal parameters as well as average values of uric acid; the HOMA Index indicated insulin resistance. Regarding the anthropometric profile, the patients were mostly overweight with a waist/hip index indicativeof an android type fatty distribution. In conclusion, the endocrine-metabolic and anthropometric profile observed corresponds to SOP, in which the state of insulin resistance shown by the HOMA index constitute the central pathophysiological axis.