Incidence and distribution of malignant solid tumors in children 0-15 years, by histological type, age and gender

Authors

  • Samaris Estrada University Centrocidental Lisandro Alavarado, Venezuela.

Keywords:

Pediatric cancer, Cancer distribution, malignant tumor, frequency

Abstract

This work aims to determine the frequency and distribution of malignant solid tumors in children aged 0-15 years, according to histological type, age and sex. Review of 17 years in the Department of Pathology, " Dr. Hans R. Döehnert” Central Hospital" Antonio Maria Pineda " during the years 1986-2003. Transverse retrospective descriptive non-experimental study was performed 247 biopsies from patients with diagnosis is a malignant solid tumor in the pathology department, " Dr. Hans R. Döehnert” university central hospital “Antonio Maria Pineda” from 1986 to 2003. Lymphomas ranked first with 76 cases (30,76 %) non-Hodgkin lymphomas , 46 cases (18,62 %) , Hodgkin's disease 30 cases (12,14 %) , second tumors are Central Nervous System (CNS ) : 33 cases ( 13,36 %), then the neuroblastomas : 30 cases (12,14 %) , Nephroblastoma ( Wilms tumor ) : 22 cases ( 8,90 %), osteosarcomas 18 cases ( 7,28% ) , Rhabdomyosarcomas : 17 cases ( 6,88 %) , germ cell tumors 10 cases ( 4,84 %) , Retinoblastoma 9 cases ( 3,64 %) , and round cell tumors 7 cases ( 2,83 ) , Ewing sarcoma 5 cases ( 2,02 %) , non-gonadal teratomas (immature ) 4 cases ( 1,60 %) , hepatoblastoma  4 patients ( 1,60 %) , Stromal cell tumors and Sex Cord 3 cases ( 1,21 %) , thyroid carcinoma 2 cases (0,80 % ) , colon adenocarcinoma 2 cases (0,80 % ), melanoma 1 case ( 0,40 %) , histiocytosis one case ( 0,40 % ) , clear cell sarcoma of kidney a case ( 0,40 % ) , hemangiopericytoma one case ( 0,40 % ) , malignant schwannoma one case ( 0,40 %). In children aged 2-6 years were more frequent lymphomas and nephroblastoma and neuroblastoma. In children aged 10-12 years were Rhabdomyosarcomas and osteosarcomas , with a predominance in males (59,6%).
 The most frequent solid tumors are malignant lymphomas , followed by CNS tumors , the most affected age group is between 2 and 6 years, with a predominance in males.

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References

1. Ahmedin Jemal; Andréa Thomas; Taylor Murray; Michael Thun: Cancer Statistics, 2002. C.A. Cancer J. Clin. 2002; 52 (1). 23 -47.
2. Alessandro Juenker; Francesca Diomedi Camassei; Renata Boldrini; Luigui De Sio; Lucilla Rava; Cesare Bosman Camilo Boglino and Alberto Donfrancesco. Renal Neoplasms of Chuildhood. A Clinicopathologic. J. of Pediatric Surgery. 2001; 36 (10): 1522 – 1527.
3. Anuarios de Epidemiología y Estadísticas Vitales. 1986 – 1999. Ministerio de Salud y Desarrollo Social. Barquisimeto. Estado Lara.
4. Boletín. Epidemiológico semanal. Incidencia y mortalidad en tumores infantiles en España. 1998 / Vol. 6. N° 20: 189 – 196.
5. Chávez Prado, Miguel Ángel. Neoplasias en Niños. Hospital Rebagliatih. Acta Cancerol. 1993; 23 (4): 40 - 5.
6. Campbell Bull, Myriam: Ferreiro C. Myrian; Bronda M. Alessandro; Wong A Carlos; Tordecilla C. Juan; Joannon S. Pilar; Rizzardini L. Carlos. Tumores Abdominales Malignos en la infancia: Orientación Diagnóstica. Rev. Chil. Pediatría. 1999; 70 (6): 464 – 9.
7. Castillo, Fuchel. Childhood Cancer in Uruguay: 1992 – 1994. Incidencia y mortalidad. Me. Pediatr. Ocol. 2001. 37 (4): 400 – 404.
8. Desandes, Enmanuel: Clavel Jacqueline; cáncer incidencia Among. Children in France, 1990 – 1999 Pediatric. Blood. Cancer. 2004; 43: 749 – 757.
9. Estrada, Samaris; Escalona, Rosi; Jiménez Luisy; Frecuencia de tumores sólidos malignos en niños según tipo histológico, edad y sexo. Boletín Médico de Postgrado. 2003 (1):2 – 8.
10. Gurney, James; Severson, Richard; Davis, Scott; Robinson, Leslie L. Incidence of Cancer in Children in the Unites States. Cancer. 1995; 8 (75): 22186 – 2195.
11. J. Stockey, L. Dehner. Pediatric Pathology, 1992, 2: 1011-1018.
12. Malcolm A. Smith; Lynn A. Gloeckeer Ries. Childhood Cancer: Incidence, Survival and Mortality. Principles and Practice of Pediatric Oncology. Fourth Edition. 2002: 1 - 20
13. Martin, Alert. Incidencia of Childhood Cancer in Cuba. (1986 – 1990) Int. J Cancer. 1997; 72 (4): 551 – 555.
14. Mejía. AJM, Flores. Edad de aparición de los diferentes tumores malignos en la infancia. Rev. Medica. IMSS. 2005. 43 (1): 25 – 38.
15. Nass de Ledo, Ingrid; Zamora de la Cabada, Mariela; Ruiz, Francis; Suárez, Alcira. Tumores Malignos en niños: Revisión Clínico patológica 1970 – 1990. Salus Militae. 1994; 19 (1/2): 21 – 8.
16. Pereira, Augusto; Santos, Soraya; Meta, Feo; Tumores sólidos en Niños y Adolescentes, Registro Hospitalarios de Cáncer. 1985 – 2001. Rev. Venez. Oncol. 2003; 15(3): 161 – 169.
17. Ries L; Eisner M; Kosary C; Eds. SEER. Cancer Statics Reviw 1973 – 1998. National Cancer Institute, Bethesda, M.D. 2001.
18. Tesis de especialista: Castro, Ciro. Tumores Sólidos en Pediatría. UCLA. Barquisimeto. 1990.
19. Young, John; Miller, Robert. Incidence of Malignant tumors in U.S. Children. J. Pediatrics. 1975; 2: 254 – 258.
20. Dimas J Garcilazo, Eduardo I Sanoja C, Lucila Sanoja C, Filomena Moschella S. Neoplasias sólidas de células redondas en edad pediátrica correlación entre diagnóstico morfológico e inmunohistoquímica Rev. Venez. Oncol. 2011. 23(3).

Published

2018-08-06

How to Cite

Estrada, S. (2018). Incidence and distribution of malignant solid tumors in children 0-15 years, by histological type, age and gender. Revista Venezolana De Salud Pública, 2(2), 29-34. Retrieved from https://revistas.uclave.org/index.php/rvsp/article/view/1469

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Artículos originales